Does Semaglutide help with mood?
Possibly — but there are few reports. 27% of 11 people who reported on Semaglutide for mood say it improved. 0% noticed no change and 73% say it got worse.
Mood: what users report
27%better11 reports · few reports
3 better0 no change8 worse
What people say about Semaglutide and mood
“I recently cycled off Ozempic after 6 months. It did not agree with me...profund depression...profound depression(something I dont normally have an issue with).”
“I’ve noticed since getting on the wegovy I have felt like I’ve been in a strange depression. I’m not explicitly suicidal but I feel nothing - no happiness, no love, no hope.”
“With semaglutide, my side effects were fatigue, depression, and very mild nausea.”
What the research says
AResearch: Strong421 meta-analyses · 307 trials on PubMed
None of the top reviews we found look specifically at mood. See all research on Semaglutide.
Side effects people mention
nausea 35fatigue 20stomach issues 11constipation 9vomiting 6
What else is Semaglutide used for?
Based on few reports — treat as anecdotal. Information only — not medical advice. How we count