PlainPill

Does SAM-E help with energy?

Yes, for most people. 87% of 23 people who reported on SAM-E for energy say it improved. 4% noticed no change and 9% say it got worse. That is about the typical result for energy (87% across 95 options).

Energy: what users report
87%better23 reports · medium confidence
20 better1 no change2 worse

Ranked #57 of 95 for energy.

What people say about SAM-E and energy

“Taking SAM-e completely changed my life from total lethargy with the only relief being Adderall or Ritalin to being a functional person, no side effects noticed and I only have to cycle it occasionally.”
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“SAMe and agmatine sulfate over the past year to be the two most noticeably helpful supplements i have ever taken for baseline energy/mood.”
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“I was taking Sam-E for an energy boost when I go for a ride. I no longer take that stuff though because I've heard it disrupts sleep patterns.”
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What the research says

BResearch: Moderate3 meta-analyses · 1 trials on PubMed

None of the top reviews we found look specifically at energy. See all research on SAM-E.

Side effects people mention

insomnia 8jitteriness 8stomach issues 5anxiety 4drowsiness 2

What else is SAM-E used for?

Information only — not medical advice. How we count

Does SAM-E help with energy? 87% of 23 users say yes — PlainPill