Does SAM-E help with pain & inflammation?
Possibly — but there are few reports. 100% of 8 people who reported on SAM-E for pain & inflammation say it improved. 0% noticed no change and 0% say it got worse.
Pain & inflammation: what users report
100%better8 reports · few reports
8 better0 no change0 worse
What people say about SAM-E and pain & inflammation
“Took me years to feel normal. Back then I used SAMe to help me.”
“Low and behold it actually worked. Within five days I noticed a difference. The headaches are gone and I wake up everyday feeling refreshed.”
“It helped mood and motivation, had more of a desire to get out and do things like be social. Felt like a weaker Wellbutrin to me.”
“Another great stack I was into awhile back was SAMe+CDP choline+fasoracetam. That's definitely a 1-2 week stack but it worked *very* nicely for a high-productivity, focused edge.”
What the research says
BResearch: Moderate3 meta-analyses · 1 trials on PubMed
None of the top reviews we found look specifically at pain & inflammation. See all research on SAM-E.
Side effects people mention
insomnia 8jitteriness 8stomach issues 5anxiety 4drowsiness 2
What else is SAM-E used for?
Based on few reports — treat as anecdotal. Information only — not medical advice. How we count