S23
People mainly take S23 for performance, weight loss, hormones. Based on 64 first-hand reports. Ranked #484 of 2,750 overall.
32
User score
Mixed22% positive16% mixed6% negative56% unclear
Of reports that state an outcome, 50% are positive.
Clinical research
Research pending
High-risk compound. SARMs are not approved as supplements, carry serious and sometimes irreversible risks, are banned in competitive sport and may be restricted where you live. Nothing here is a recommendation to use it.
What S23 does, according to users
Of the people who reported each effect, the share who said it got better.
7 more with fewer than 3 reports
betterno changeworse
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
Research data for S23 is being compiled.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
30 mgas reported
6 weeksas reported
10 mg2x daily
15-20 mgdaily, split into two doses
10 mgsplit into 2 doses
40 mgdaily
Reported side effects
How often each side effect came up across all reports.
suppression ×17acne ×3hair loss ×3night sweats ×2aggression ×2testicular atrophy ×1cramping ×1elevated liver ×1
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“I also run testosterone replacement with the SARM S-23.”
“No reason to stackc rad and s23 because they hit the same receptors....”
“Steer clear of yk11, s23”
“Or if you're ambitious an S23/LGD3303 cycle for 6 weeks respectively.”
“Are more such as: S4, S23, SR9009, LGD 3033, LGD 2033, YK11, GW 501516.”
Top discussions (5)
- Stacking up on Yk-11, MK-677, Rad-140, and S-23. Any thoughts or concerns I should be worried about? Including TRT, and Microdosing IGF 100mcmg’s a day. ↗
- what are some peptides that show physical changes to the body? ↗
- List of SARMs (known) half life and how much you will have in your body ↗
- ExpressPCT - Big news on SARMS! ↗
- This is how I put together my cycles (warning this is a long read but still good for newbies) ↗
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User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate