PlainPill
Substance

Psilocybin Cubensis

Based on 3 first-hand reports and 1 meta-analyses & systematic reviews in the medical literature. Ranked #3341 of 4,149 overall.

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6
User score
Not enough data
0% positive0% mixed0% negative100% unclear

Of reports that state an outcome, 0% are positive.

Clinical research
BModerate research base
1
meta-analyses
0
RCTs
0
papers

What Psilocybin Cubensis does, according to users

Of the people who reported each effect, the share who said it got better.

No specific effects reported yet.
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

BModerate research base

At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.

J Psychoactive Drugs · 2025 · Meta-analysis / systematic review
Pharmacokinetics of Psilocybin, a Tryptamine Alkaloid in Magic Mushroom (Psilocybe cubensis): A Systematic Review

Conclusion: Psilocin is metabolized primarily through both Phase I and Phase II processes with the half-life of 2-3 hours. This review also identified lack of some pharmacokinetic related information and limitations of available research that may help direct future investigations to better understand the pharmacokinetics and improve study design including dose selection and dosage optimization.

PubMed 39257234 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

0.3 g1 day on, 2 days off
0.1-1 g5 days on 2 days off
1 gin blend, throughout day

Reported side effects

How often each side effect came up across all reports.

tolerance ×1

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

No first-hand experiences with a clear outcome yet.
Top discussions (3)

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User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate