What are the side effects of Pregabalin?

Users most often report dependence, cognitive impairment, brain fog, withdrawal, fatigue. Side effects came up 35 times across 102 reports.

User reports can't establish safety. PubMed lists 387 meta-analyses and 599 randomized trials. Talk to a doctor or pharmacist, especially if you take other medication.

Pregabalin side effects

Across 102 first-hand reports, people mentioned a side effect 35 times (about 34 per 100 reports). The most common: dependence, cognitive impairment, brain fog. User reports show what people notice — they can't tell you whether Pregabalin is safe for you.

Reported side effects

dependence7

cognitive impairment6

brain fog5

withdrawal5

fatigue4

drowsiness4

forgetfulness2

cognitive decline2

What got worse for some people

Focus63% worse · 38% better · of 8

In their own words

“I’ve since trialled Pregabalin and currently been on Lamotrigine for 7 weeks and zero improvement.”

Didn't helpRead the discussion ↗

“Pregabaline helps but I think my dose is too low I take between 200-300 and I’m waiting for my appointment and see if it will get increased.”

MixedRead the discussion ↗

“I am prescribed pregablin, one 25mg tablet at night. But I can't focus while on that, so can only take it at night.”

Didn't helpRead the discussion ↗

“I've tried seizure meds, which help to an extent, but they have awful side effects... I'd have to live with the edema from the Lyrica. I never went back and stopped taking the Lyrica.”

MixedRead the discussion ↗

“Best results I got with pregabalin, phenibut and sometimes some benzos...Pregabalin makes you feel a little stupid (hard to recall words, you feel like you're slurring your speech) at a dose where it's actually working for motivation and anxiolytic effects (~100-150mg in my case)”

MixedRead the discussion ↗

“PRN: Pregabalin 50mg 3x/day (can make me sad/tired/loopy, worsening EF and thus worsening anxiety).”

MixedRead the discussion ↗

Is Pregabalin safe? What the research covers

AResearch: Strong387 meta-analyses · 599 randomized trials on PubMed

Eur Neuropsychopharmacol · 2017

How addictive are gabapentin and pregabalin? A systematic review

Conclusion: Pure overdoses of gabapentinoids appeared to be relative safe but can become lethal (pregabalin > gabapentin) in mixture with other psychoactive drugs, especially opioids again and sedatives. Based upon these results, we compared the addiction risks of gabapentin and pregabalin with those of traditional psychoactive substances and recommend that in patients with a history of SUD, gabapentinoids should be avoided or if indispensable, administered with caution by using a strict therapeutic and prescription monitoring.