PlainPill

Pre

Based on 3 first-hand reports and 21,340 meta-analyses & systematic reviews in the medical literature. Ranked #1257 of 3,539 overall.

22
User score
Mostly positive
67% positive0% mixed0% negative33% unclear

Of reports that state an outcome, 100% are positive.

Clinical research
AStrong research base
21,340
meta-analyses
41,110
RCTs
966,007
papers

What Pre does, according to users

Of the people who reported each effect, the share who said it got better.

No specific effects reported yet.
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Ageing Res Rev · 2021 · Meta-analysis / systematic review
Prevalence of multidimensional frailty and pre-frailty in older people in different settings: A systematic review and meta-analysis

Conclusion: In conclusion, frailty and pre-frailty, according to a multidimensional definition, are common in older people affecting, respectively, one person over four and one over three. Our work further strengths the importance of screening frailty in older people using a multidimensional approach.

PubMed 34700009 ↗
Front Public Health · 2024 · Meta-analysis / systematic review
A systematic review and meta-analysis of breastfeeding and neurodevelopmental outcomes in preterm infant

Conclusion: Our systematic review supports current recommendations for breastfeeding in preterm infants, emphasizing its positive effects on cognitive abilities and reduced risk of neurodevelopmental disorders. Further studies are needed to clarify if DHM provides neurodevelopmental benefits comparable to maternal milk, as current evidence does not sufficiently address this question. Additionally, future investigations should prioritize refining our understanding of the influence of breastfeeding on motor development in this vulnerable population.

PubMed 39639909 ↗
BMJ · 2016 · Meta-analysis / systematic review
Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies

Conclusion: There are several practical clinical risk factors that, either alone or in combination, might identify women in early pregnancy who are at "high risk" of pre-eclampsia. These data can inform the generation of a clinical prediction model for pre-eclampsia and the use of aspirin prophylaxis in pregnancy.

PubMed 27094586 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

pre-workoutas reported

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

More supplements

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate