Conclusion: Here, we perform a systematic analysis of studies assessing the mechanisms of action of various herbal medicines on different subtypes of GABA receptors in the context of sleep control. Currently available evidence suggests that herbal extracts may exert some of their hypnotic and anxiolytic activity through interacting with GABA receptors and modulating GABAergic signaling in the brain, but their mechanism of action in the treatment of insomnia is not completely understood.
Does Passionflower help with sleep?
Yes, for most people. 85% of 46 people who reported on Passionflower for sleep say it improved. 11% noticed no change and 4% say it got worse. That is about the typical result for sleep (82% across 71 options).
Sleep: what users report
85%better46 reports · medium confidence
39 better5 no change2 worse
Ranked #27 of 71 for sleep.
What people say about Passionflower and sleep
“St. John's Wort, Passion Flower, Hops, and Skullcap. My sleep improved with those.”
“Some things didn't work at all for me: melatonin (tried 1mg-10mg), passionflower.”
“I take 2 teaspoons Mag Citrate...and a half a dropper to dropper of Passionflower extract...Works every time.”
“Man do I love that Passionflower in Vignatex. Makes me feel like a mellow jellow... From my personal experience it hits me pretty hard with drowsiness.”
What the research says
BResearch: Moderate10 meta-analyses · 8 trials on PubMed
Nutrients · 2021
Herbal Remedies and Their Possible Effect on the GABAergic System and SleepSide effects people mention
drowsiness 8agitation 2qt prolongation 1stimulation 1nausea 1
What else is Passionflower used for?
Information only — not medical advice. How we count