Conclusion: Varied outcomes of analyzed dietary interventions may be due to the heterogeneous thyroid condition, high variability between patients, and differences in habitual intake of critical nutrients (e.g., iodine, selenium, and iron) in different populations. Therefore, there is a great need for further experimental studies to determine whether any nutritional interventions are beneficial in Hashimoto's disease.
PubMed 36839399 ↗Nigella Sativa
People mainly take Nigella Sativa for anxiety, mood, immunity. Based on 22 first-hand reports and 67 meta-analyses & systematic reviews in the medical literature. Ranked #456 of 1,974 overall.
Of reports that state an outcome, 66% are positive.
What Nigella Sativa does, according to users
Of the people who reported each effect, the share who said it got better.
6 more with fewer than 3 reports
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Conclusion: There is moderate to high level of evidence from randomized controlled trials that the Ayurvedic herbs guggulu, garlic, and black cumin are moderately effective for reducing hypercholesterolemia. In addition, minimal evidence was found for any side effects associated with these herbs, positioning them as safe adjuvants to conventional treatments.
PubMed 34071454 ↗Conclusion: Supplementations with green tea (MD: -1.25 kg, 95%CI: -1.68, -0.82) and glucomannan (MD: -1.36 kg, 95%CI: -2.17, -0.54) demonstrated small weight loss, also the certainty of evidence was rated low. Based on our findings, supplementations with nutraceuticals can result in a small weight loss in adults with overweight or obesity.
PubMed 37778464 ↗Conclusion: Supplementation with N. sativa exerts a moderate effect on reduction in body weight, BMI and WC. However, due to the high heterogeneity for body weight and limited high quality studies, the findings should be declared by caution. No serious side effects were also reported following N. sativa supplementation. Further studies are needed to clarify the effects of N. sativa on other anthropometric indices.
PubMed 29559374 ↗Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Nigella Sativa | 400mg (5% Thymoquinone)”
“plan to buy nigella sativa soon, as I heard it recommended elsewhere.”
“I use it for allergy issues and it works great. Noticed bad moods consistently after consuming it so I stopped”
“the next best thing in my opinion is Nigella Sativa”
“Nigella sativa causes an 15-25% increase in logical memory and 30 minute recall”
Top discussions (5)
- Simple HRV & Sleep Promoting Stack [Oura Data Included] ↗
- How to fix severe hippocampus damage? ↗
- Nigella sativa causes an 15-25% increase in logical memory and 30 minute recall ↗
- Nigella Sativa enhances rate of learning, short delay free recall and long delay free recall in adolescent males ↗
- Nigella Sativa sublingual is the most effective thing I have taken for acute mood stability and reduction of anxiety. ↗
Other options for anxiety
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate