PlainPill

Niacin side effects

Across 269 first-hand reports, people mentioned a side effect 43 times (about 16 per 100 reports). The most common: flushing, flush, stomach issues. User reports show what people notice — they can't tell you whether Niacin is safe for you.

Reported side effects

flushing29
flush5
stomach issues2
liver damage2
niacin flush2
elevated liver1
blood sugar1
irritability1

What got worse for some people

In their own words

“If you over methylate, niacin may also help you. Binds to free methyl groups... It's how I fixed my heart palpitations after taking methylsulfonymethan.”
HelpedRead the discussion ↗
“Been taking Niacin, but other than the flush, I've found it makes me feel kinda irritable after taking it and my stomach doesn't feel great.”
MixedRead the discussion ↗
“it takes close to 10 grams of niacin a day to tame my symptoms and have me feeling good.”
HelpedRead the discussion ↗
“I've been megadosing Niacin for a couple of years and anecdotally feel like it's improving my health.”
HelpedRead the discussion ↗
“Had bad flushing w/ the niacin. Felt like I was on fire, massive blotching covered entire body.”
MixedRead the discussion ↗
“Ever since I started taking niacin daily it's greatly reduced the frequency and intensity of them, but you have to get the flushing kind.”
HelpedRead the discussion ↗

Is Niacin safe? What the research covers

AResearch: Strong114 meta-analyses · 379 randomized trials on PubMed
Clin Nutr · 2022
ESPEN micronutrient guideline

Conclusion: This guideline should enable addressing suboptimal and deficient status of a bundle of MNs in at-risk diseases. In particular, it offers practical advice on MN provision and monitoring during nutritional support.

Clin Nutr · 2021
Intake and adequacy of the vegan diet. A systematic review of the evidence

Conclusion: Following a vegan diet may result in deficiencies in micronutrients (vitamin B12, zinc, calcium and selenium) which should not be disregarded. However, low micro- and macronutrient intakes are not always associated with health impairments. Individuals who consume a vegan diet should be aware of the risk of potential dietary deficiencies.

Niacin side effects: what 269 users report — PlainPill