PlainPill

Neuropeptide S

Based on 3 first-hand reports and 1 meta-analyses & systematic reviews in the medical literature. Ranked #2880 of 3,539 overall.

6
User score
Not enough data
0% positive0% mixed0% negative100% unclear

Of reports that state an outcome, 0% are positive.

Clinical research
BModerate research base
1
meta-analyses
1
RCTs
425
papers
High-risk compound. Peptides are not approved as supplements, carry serious and sometimes irreversible risks, are banned in competitive sport and may be restricted where you live. Nothing here is a recommendation to use it.

What Neuropeptide S does, according to users

Of the people who reported each effect, the share who said it got better.

No specific effects reported yet.
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

BModerate research base

At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.

Behav Brain Funct · 2026 · Meta-analysis / systematic review
Neuropeptide S modulation of learning and memory: a systematic review

Conclusion: The Neuropeptide S system emerges as a critical modulator of memory processes. The NPS signaling may preferentially influence learning that involves emotionally or motivationally relevant stimuli. This highlights the NPS system's potential as a target for therapeutic interventions for particular memory impairments.

PubMed 42069596 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

No doses stated in the reports so far.

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

More peptides

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate