Across 132 first-hand reports, people mentioned a side effect 8 times (about 6 per 100 reports). The most common: green urine, color change, agitation. User reports show what people notice — they can't tell you whether Methylene Blue is safe for you.
“First thing I noticed was mental clarity, not jittery like caffeine, just cleaner focus.”
“I have noted really good benefits since day 1. I have been breathing much better...mental clarity. I cannot name any notably bad reactions.”
“Things I've tried with no improvement: Piracetam, Phenylpiracetam, Modafinil, methylene blue, Noopept”
“i took methylene blue and vyvanse together. Didnt do much, other than cause a little bit of insomnia”
Conclusion: Among critically ill adults with septic shock, based on low-certainty evidence, MB may reduce short-term mortality, duration of vasopressors, and hospital length of stay, with no evidence of increased adverse events. Rigorous randomized trials evaluating the efficacy of MB in septic shock are needed.