The short answer. There isn't much data on Lactobacillus Acidophilus yet — 3 mentions, 0 with a clear outcome — so treat these numbers as anecdotal. It is well studied — 55 meta-analyses on PubMed.
From 3 mentions in total — the rest didn't say how it went and aren't counted.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: alternative or complementary treatments; douching; drug treatments; garlic; intravaginal preparations (nystatin, imidazoles, tea tree oil); oral fluconazole; oral itraconazole; and yoghurt containing Lactobacillus acidophilus (oral or intravaginal).
PubMed 25775428 ↗Conclusion: In this systematic review we present information relating to the effectiveness and safety of the following interventions: alternative or complementary treatments, douching, drug treatments, garlic, intravaginal preparations (boric acid, nystatin, imidazoles, tea tree oil), oral fluconazole, oral itraconazole, treating a male sexual partner, and yoghurt containing Lactobacillus acidophilus (oral or vaginal).
PubMed 19454049 ↗Conclusion: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: alternative or complementary treatments; douching; drug treatments; garlic; intravaginal preparations (boric acid, nystatin, imidazoles, tea tree oil); oral fluconazole; oral itraconazole; treating a male sexual partner; and yoghurt containing Lactobacillus acidophilus (oral or vaginal).
PubMed 21718579 ↗Conclusion: However, it was statistically significant on day 3. When administered at a dosage of more than 109 CFU to children with acute gastroenteritis, moderate- to low-quality data showed that Lactobacillus acidophilus reduced the duration of diarrhea and conferred a benefit for frequency of diarrhea.
PubMed 35277042 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.
“I think most probiotics contain acidophilus, generally good for digestion.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate