PlainPill

Gynostemma

People mainly take Gynostemma for mood. Based on 9 first-hand reports and 5 meta-analyses & systematic reviews in the medical literature. Ranked #2920 of 4,149 overall.

10
User score
Not enough data
0% positive0% mixed11% negative89% unclear

Of reports that state an outcome, 0% are positive.

Clinical research
AStrong research base
5
meta-analyses
11
RCTs
601
papers

What Gynostemma does, according to users

Of the people who reported each effect, the share who said it got better.

betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Cochrane Database Syst Rev · 2013 · Meta-analysis / systematic review
Herbal medicines for fatty liver diseases

Conclusion: Some herbal medicines seemed to have positive effects on aspartate aminotransferase, alanine aminotransferase, ultrasound, and computed tomography. We found no significant difference on adverse effects between herbal medicine and control groups. The findings are not conclusive due to the high risk of bias of the included trials and the limited number of trials testing individual herbal medicines. Accordingly, there is also high risk of random errors.

PubMed 23975682 ↗
Am J Chin Med · 2023 · Meta-analysis / systematic review
The Role of Gynostemma pentaphyllum in Regulating Hyperlipidemia

Conclusion: Furthermore, GPE treatment markedly changed the intestinal microbiota structure and constitution of tryptophan metabolites. In conclusion, our results confirm the lipid-lowering effect of GP, which may be partly attributable to regulation of the intestinal microbiota and tryptophan metabolism.

PubMed 37129524 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

as teaas reported
500 mgmorning
dailyas reported

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

Other options for mood

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate