PlainPill
Supplement

Gold Standard

Based on 3 first-hand reports and 3,413 meta-analyses & systematic reviews in the medical literature. Ranked #2001 of 3,539 overall.

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14
User score
Mixed
33% positive67% mixed0% negative0% unclear

Of reports that state an outcome, 33% are positive.

Clinical research
AStrong research base
3,413
meta-analyses
2,058
RCTs
114,957
papers

What Gold Standard does, according to users

Of the people who reported each effect, the share who said it got better.

No specific effects reported yet.
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Phys Ther Sport · 2025 · Meta-analysis / systematic review
Effect of open kinetic chain exercises during the first weeks of anterior cruciate ligament reconstruction rehabilitation: A systematic review and meta-analysis

Conclusion: The evidence suggests that OKC exercises may provide benefits and no adverse effects in the early stages of rehabilitation after ACL-R, particularly when initiated after CKC exercises. These findings are consistent with current clinical practice guideline recommendations for the inclusion of OKC in rehabilitation programs.

PubMed 39985872 ↗
J Int Med Res · 2023 · Meta-analysis / systematic review
Comparison of holmium laser enucleation and transurethral resection of prostate in benign prostatic hyperplasia: a systematic review and meta-analysis

Conclusion: HoLEP was associated with significantly lower risk of hyponatremia, blood transfusion, and urethral stricture but greater risk of postoperative dysuria. Compared with TURP, HoLEP had better curative efficacy at 6, 12, and 24 months after operation and lower incidence of adverse events in patients with BPH.

PubMed 37561537 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

dailyas reported

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

“I've used Optimum Nutrition Gold Standard forever, and they all taste great to me”
HelpedRead the discussion ↗
Top discussions (3)

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User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate