People mainly take Ghb for sleep. Based on 14 first-hand reports and 31 meta-analyses & systematic reviews in the medical literature. Ranked #441 of 1,974 overall.
Of reports that state an outcome, 51% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Our study demonstrates the high prevalence of chemsex and sexualized drug use among MSM, emphasizing the urgent need for comprehensive education on substance-related risks to encourage safer sex practices.
PubMed 40759067 ↗Conclusion: A minority of MSM appear to engage in chemsex behaviours but they are at risk of this negatively impacting on their health and well-being. Further research is required to examine high risk chemsex behaviours, impact of chemsex on psycho-social well-being and if chemsex influences uptake of PrEP, PEP and sexual health screening.
PubMed 30513473 ↗Conclusion: GHB was effective in improving narcolepsy-cataplexy and related symptoms in adults but was less well tolerated than placebo because of dose-dependent side effects.
PubMed 31671326 ↗Conclusion: The manufacturer's recommended cutoff is conservative but more reliable at categorising G6PD deficient individuals than those based on calculations of 30% activity using the AMM. The observed decrease in G6PD activity in children between 1 and 5 years of age warrants further investigation.
PubMed 41261454 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“Useth ghb instead of alcohol and thee nev'r has't a hangov'r again”
“GHB (legality may be an issue) is a somewhat alcohol like feeling minus the terrible hangover”
“GHB is also a really fantastic GABA agonist, but it definitely will cause rebound symptoms and it is definitely addictive, much like phenibut.”
“Take some GHB instead of alcohol, imo better subsitute then alcohol if used responsibly. And no hang-over”
“GHB is what you're looking for OP. Very similar to the alcohol high but with less mind fog and zero hangover, great drug.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate