Across 167 first-hand reports, people mentioned a side effect 17 times (about 10 per 100 reports). The most common: drowsiness, brain fog, fatigue. User reports show what people notice — they can't tell you whether CBD Oil is safe for you.
“usual recommendations: CBD oil, ashwaghanda, valerian, lemon balm, theanine, GABA and about a half dozen others. Ashwaghanda helped with my stress and levels and lemon balm and theanine had a mild effect but that's about it.”
“4 month experiment with CBD oil for sleep a year and a half ago yielded a near-total blackout of my mental overlays, resulting in depersonalization and disorientation.”
“Within 20 minutes I could feel a softness gradually washing over my brain. It was incredibly gentle and soft as if the CBD was telling me everything was going to be okay.”
“Probably most notable for anxiety and the cognitive benefits that come from treating the anxiety like other nootropics. I also believe it has anti-inflammatory properties too.”
“i've tried CBD oil, black seed oil and NAC to help with the glutamate / gaba imbalance but I can't say any of these have significantly made my symptoms better.”
“I've taken pure cbd in the past, for very long periods of time, and it helped a lot with inflammation, and seemed to be anxiolitic as well.”
Conclusion: Altogether, insufficient evidence exists on the efficacy and safety of CBD oil in schizophrenia patients. More RCTs, comparing CBD oil with placebo and other antipsychotics are warranted.
Conclusion: CBD is considered safe for treating canine OA. CBD may reduce pain scores, but the evidence is very uncertain to conclude its clinical efficacy. High-quality clinical trials are needed to further evaluate the roles of CBD in canine OA.
Conclusion: Drug-drug interactions with cannabinoids are likely amongst prescription medications that use common CYP450 systems. Our findings highlight the need for healthcare providers and patients/care-givers to openly communicate about cannabis/cannabinoid use to prevent unintended adverse events. To that end, we have developed a free online tool (www.CANN-DIR.psu.edu) to help identify potential cannabinoid drug-drug interactions with prescription medications.