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Does Berberine help with mood?

Possibly — but there are few reports. 87% of 15 people who reported on Berberine for mood say it improved. 0% noticed no change and 13% say it got worse.

Mood: what users report
87%better15 reports · few reports
13 better0 no change2 worse

What people say about Berberine and mood

“I started berberine for high blood sugar but quickly noticed mood and energy enhancing effects from it. I've been taking 500 mg daily...I experienced the worst gastrointestinal issues ever, pure yellow diarrhea and smelly piss.”
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“I feel really really happy, I keep dancing lol. Probably placebo, but I didn't expect feel good mood benefits!”
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What the research says

AResearch: Strong109 meta-analyses · 110 trials on PubMed

None of the top reviews we found look specifically at mood. See all research on Berberine.

Side effects people mention

stomach issues 13constipation 3anxiety 3brain fog 2irritability 2

What else is Berberine used for?

Based on few reports — treat as anecdotal. Information only — not medical advice. How we count

Does Berberine help with mood? 87% of 15 users say yes — PlainPill