J Head Trauma Rehabil · 2018
Branched Chain Amino Acids (BCAAs) and Traumatic Brain Injury: A Systematic ReviewConclusion: Although our review demonstrates an overall positive association between BCAAs and TBI outcome, the evidence of the efficacy of supplementation has been limited to severe TBI. To date, there is insufficient evidence to determine the benefits of BCAAs in mild TBI. Given the high frequency of mild TBI and the promise of BCAAs as an intervention in severe TBI, future research should examine the effects of BCAAs in milder brain injury.