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B Vitamins side effects

Across 180 first-hand reports, people mentioned a side effect 12 times (about 7 per 100 reports). The most common: anxiety, insomnia, jitteriness. User reports show what people notice — they can't tell you whether B Vitamins is safe for you.

Reported side effects

anxiety4
insomnia2
jitteriness1
overmethylation1
keep awake1
b6 toxicity1
headache1
nausea1

What got worse for some people

In their own words

“When I get enough or too much B vitamins I can't sleep.”
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“I’ve tried lemon balm, b vitamins, magnesium glycinate, weed, so many things for anxiety. Nothing came close to that drip!”
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“I’ve already tried a lot of things some basic things like magnesium, zinc, B vitamins, and PEA, tyrosine, theanine, nac, inositol, creatine, glycine, cafeine, without major results.”
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“I've tried switching meds, a few b vitamins, tyrosine but nothing seems to help.”
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“I've tried tyrosine and stimulating adaptogens (panax and rhodiola) and alcar and b-vitamins and TMG but nothing works.”
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Is B Vitamins safe? What the research covers

AResearch: Strong107 meta-analyses · 248 randomized trials on PubMed
Nutr Rev · 2022
B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis

Conclusion: This meta-analysis suggests that B vitamin supplementation is associated with slowing of cognitive decline, especially in populations who received early intervention and intervention of long duration; the study also indicates that higher intake of dietary folate, but not B12 or B6, is associated with a reduced risk of incident dementia in non-dementia aged population. Given the prevalence of dementia cases in many countries with aging populations, public health policies should be introduced to ensure that subgroups of the population at risk have an adequate B vitamin status.

Arch Gynecol Obstet · 2024
A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, and lycopene in relation to increased morbidity in women after menopause

Conclusion: In conclusion, maintaining optimum serum levels of nutrients and vitamins, either through a balanced and healthy diet consuming fresh fruits, vegetables, and fats or by taking appropriate supplementation, is essential in maintaining optimal health-related quality of life and reducing the risk for women during the menopausal transition and after menopause. Nevertheless, more recent studies need to be assessed to formulate adequate recommendations to achieve positive clinical outcomes.

B Vitamins side effects: what 180 users report — PlainPill