Eur Neuropsychopharmacol · 2024 · Meta-analysis / systematic review
Network meta-analysis (NMA) of dextromethorphan-bupropion (AXS-05) efficacy and safety in major depressive disorderPubMed 38917770 ↗Auvelity
People mainly take Auvelity for anxiety. Based on 6 first-hand reports and 1 meta-analyses & systematic reviews in the medical literature. Ranked #2948 of 4,149 overall.
9
User score
Mixed0% positive17% mixed0% negative83% unclear
Of reports that state an outcome, 0% are positive.
Clinical research
BModerate research base
1
meta-analyses
0
RCTs
29
papers
What Auvelity does, according to users
Of the people who reported each effect, the share who said it got better.
betterno changeworse
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
BModerate research base
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
45 mg dxm + 100 mg bupropiondaily
1 tabdaily
Reported side effects
How often each side effect came up across all reports.
No side effects reported so far.
What users say
First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.
No first-hand experiences with a clear outcome yet.
Top discussions (5)
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User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate