What are the side effects of Antihistamines?

Users most often report muscle loss, memory impairment, dizziness, hangover, destroys erections. Side effects came up 6 times across 15 reports.

Antihistamines side effects

Q: Is Antihistamines safe?

User reports can't establish safety. PubMed lists 367 meta-analyses and 590 randomized trials. Talk to a doctor or pharmacist, especially if you take other medication.

Across 15 first-hand reports, people mentioned a side effect 6 times (about 40 per 100 reports). The most common: muscle loss, memory impairment, dizziness. User reports show what people notice — they can't tell you whether Antihistamines is safe for you.

Reported side effects

muscle loss1

memory impairment1

dizziness1

hangover1

destroys erections1

next day1

In their own words

“Antihistamines are an effective vasoconstrictor, and they were my most effective tool. ... within two years of nearly constant use, I was a space case.”

HelpedRead the discussion ↗

“What I've tried: antihistamines, low histamine diet, strict keto diet. Nothing really helped.”

Didn't helpRead the discussion ↗

“Antihistamines knock me out cold all night, but makes me feel terrible the next day and destroy erections.”

MixedRead the discussion ↗

“I tried many of the things suggested to rectify this...antihistamines, ashwaganda and other cortisol lowering supplements. Even prescription sleep meds wernt working for me”

Didn't helpRead the discussion ↗

“I tried lots of different medications and they don’t really help and they also made me lose muscle.”

Didn't helpRead the discussion ↗

Is Antihistamines safe? What the research covers

AResearch: Strong367 meta-analyses · 590 randomized trials on PubMed

J Allergy Clin Immunol · 2020

Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis

Conclusion: After diagnosis and treatment of anaphylaxis, all patients should be kept under observation until symptoms have fully resolved. All patients with anaphylaxis should receive education on anaphylaxis and risk of recurrence, trigger avoidance, self-injectable epinephrine education, referral to an allergist, and be educated about thresholds for further care.