Propranolol vs Tadalafil for heart & lipids
Short answer: For heart & lipids, more users report improvement with Propranolol — 100% of 12 reports, versus 95% of 22 for Tadalafil.
Propranolol has 268 meta-analyses and 1,961 randomized trials on PubMed; Tadalafil has 120 and 347.
Based on 166 reports about Propranolol and 253 about Tadalafil. Not medical advice.
| Propranolol Medication | Tadalafil Medication | |
|---|---|---|
| Users say it helped | 79%helped105 reports · high confidence | 77%helped142 reports · high confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 268 / 1,961 | 120 / 347 |
| Mainly used for | ||
| Anxiety % reporting improvement | 94% (101) | 75% (4) |
| Libido % reporting improvement | — | 91% (99) |
| Performance % reporting improvement | 100% (2) | 97% (69) |
| Heart & lipids % reporting improvement | 100% (12) | 95% (22) |
| Mood % reporting improvement | 20% (5) | 100% (10) |
| Common side effects | insomnia, depression, fatigue, weight gain | headache, stuffy nose, heartburn, lower back |
| Typical dose reported | Not listed | Not listed |
In this systematic review and network meta-analysis, mirtazapine, biperiden, and vitamin B6 were associated with the greatest efficacy for AIA, with vitamin B6 having the best efficacy and tolerance profile. Trazodone, mianserin, and propranolol appeared as effective alternatives with slightly less favorable efficacy and tolerance profiles. These findings should assist prescribers in selecting an appropriate medication for treating AIA.
JAMA Netw Open, 2024 ↗“I just got a script for propranolol that I can take as needed and it's been a game changer.”
Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients' sexual confidence. Furthermore, patients and their partners prefer tadalafil to sildenafil. Hence, tadalafil may be a better choice for ED treatment.
Int Urol Nephrol, 2017 ↗“After a week of 2.5 mg twice a day, this is my favourite drug ever. My brain fog has gone...My mood is so much better, similar to an SSRI but without the flat feeling.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate