PlainPill

Modafinil vs Piracetam for focus

Short answer: For focus, more users report improvement with Modafinil — 86% of 689 reports, versus 80% of 458 for Piracetam.

Modafinil has 155 meta-analyses and 297 randomized trials on PubMed; Piracetam has 119 and 117.

Based on 1,613 reports about Modafinil and 1,463 about Piracetam. Not medical advice.

Modafinil
Medication
Piracetam
Supplement
Users say it helped50%helped936 reports · high confidence53%helped688 reports · high confidence
Verdict
Mixed
Mixed
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs155 / 297119 / 117
Mainly used for
Focus
% reporting improvement
86% (689)80% (458)
Energy
% reporting improvement
93% (485)78% (69)
Memory
% reporting improvement
71% (31)89% (241)
Mood
% reporting improvement
64% (125)74% (116)
Anxiety
% reporting improvement
30% (87)86% (57)
Common side effectsinsomnia, anxiety, headache, toleranceheadache, drowsiness, irritability, insomnia
Typical dose reportedNot listed250 mg / daily
Modafinil
Latest review conclusion

Our findings represent the most comprehensive available evidence base to inform patients, families, clinicians, guideline developers, and policymakers on the choice of ADHD medications across age groups. Taking into account both efficacy and safety, evidence from this meta-analysis supports methylphenidate in children and adolescents, and amphetamines in adults, as preferred first-choice medications for the short-term treatment of ADHD. New research should be funded urgently to assess long-term effects of these drugs.

Lancet Psychiatry, 2018 ↗
What a user said
“It did make me focused and alert. I was working two jobs at the time and needed every ounce of energy I could muster.”
Full Modafinil profile →
Piracetam
Latest review conclusion

High-level evidence related to pharmacological strategies for managing Lewy body dementia is rare. Strategies for important areas of need in Lewy body dementia, such as autonomic symptoms and caregiver burden, have not been investigated, nor have the views of patients and caregivers about pharmacological strategies.

Am J Psychiatry, 2015 ↗
What a user said
“The effects were wonderful, they still are to me-- verbal fluidity, increased motivation, quicker thinking, better recall, pro social, wake up in the morning with ZERO grogginess.”
Full Piracetam profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate