PlainPill

Modafinil vs Oxiracetam for focus

Short answer: For focus, users rate them about the same: 86% report improvement with Modafinil (689 reports) and 90% with Oxiracetam (148 reports).

Modafinil has 155 meta-analyses and 297 randomized trials on PubMed; Oxiracetam has 5 and 19.

Based on 1,613 reports about Modafinil and 495 about Oxiracetam. Not medical advice.

Modafinil
Medication
Oxiracetam
Supplement
Users say it helped50%helped936 reports · high confidence66%helped218 reports · high confidence
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs155 / 2975 / 19
Mainly used for
Focus
% reporting improvement
86% (689)90% (148)
Energy
% reporting improvement
93% (485)95% (37)
Mood
% reporting improvement
64% (125)68% (22)
Anxiety
% reporting improvement
30% (87)64% (14)
Sleep
% reporting improvement
21% (94)—
Common side effectsinsomnia, anxiety, headache, toleranceirritability, insomnia, headache, hypomania
Typical dose reportedNot listed1500-2250 mg / daily
Modafinil
Latest review conclusion

Our findings represent the most comprehensive available evidence base to inform patients, families, clinicians, guideline developers, and policymakers on the choice of ADHD medications across age groups. Taking into account both efficacy and safety, evidence from this meta-analysis supports methylphenidate in children and adolescents, and amphetamines in adults, as preferred first-choice medications for the short-term treatment of ADHD. New research should be funded urgently to assess long-term effects of these drugs.

Lancet Psychiatry, 2018 ↗
What a user said
“It did make me focused and alert. I was working two jobs at the time and needed every ounce of energy I could muster.”
Full Modafinil profile →
Oxiracetam
Latest review conclusion

This study enhances the understanding of the relative benefits and risks associated with various VaD treatments, providing a valuable reference for clinical decision-making.

Front Pharmacol, 2024 ↗
What a user said
“Oxi gave me a significant increase in focus, to the point where I could work for 2-3 hours without even checking facebook. / It also helped me with memory (was clearly retaining more info in both short-term and long-term).”
Full Oxiracetam profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate