Magnesium vs Propranolol for heart & lipids
Short answer: For heart & lipids, users rate them about the same: 96% report improvement with Magnesium (26 reports) and 100% with Propranolol (12 reports).
Magnesium has 82 meta-analyses and 210 randomized trials on PubMed; Propranolol has 268 and 1,961.
Based on 2,391 reports about Magnesium and 166 about Propranolol. Not medical advice.
| Magnesium Supplement | Propranolol Medication | |
|---|---|---|
| Users say it helped | 73%helped956 reports · high confidence | 79%helped105 reports · high confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 82 / 210 | 268 / 1,961 |
| Mainly used for | ||
| Sleep % reporting improvement | 88% (430) | 40% (5) |
| Anxiety % reporting improvement | 90% (289) | 94% (101) |
| Mood % reporting improvement | 82% (118) | 20% (5) |
| Energy % reporting improvement | 75% (83) | — |
| Focus % reporting improvement | 80% (45) | 100% (4) |
| Common side effects | diarrhea, drowsiness, stomach issues, vivid dreams | insomnia, depression, fatigue, weight gain |
| Typical dose reported | 500 mg / daily | Not listed |
This review confirms that the quality of literature is substandard for physicians to make well-informed recommendations on usage of oral magnesium for older adults with insomnia. However, given that oral magnesium is very cheap and widely available, RCT evidence may support oral magnesium supplements (less than 1 g quantities given up to three times a day) for insomnia symptoms.
BMC Complement Med Ther, 2021 ↗“after supplementing with 400mg of Magnesium daily. Winter blues hit me hard and my multivitamin wasn't doing any justice, but once I began supplementing Magnesium, everything changed.”
In this systematic review and network meta-analysis, mirtazapine, biperiden, and vitamin B6 were associated with the greatest efficacy for AIA, with vitamin B6 having the best efficacy and tolerance profile. Trazodone, mianserin, and propranolol appeared as effective alternatives with slightly less favorable efficacy and tolerance profiles. These findings should assist prescribers in selecting an appropriate medication for treating AIA.
JAMA Netw Open, 2024 ↗“I just got a script for propranolol that I can take as needed and it's been a game changer.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate