Magnesium L-Threonate vs Methylene Blue for focus
Short answer: For focus, users rate them about the same: 97% report improvement with Magnesium L-Threonate (109 reports) and 100% with Methylene Blue (23 reports).
Magnesium L-Threonate has 82 meta-analyses and 210 randomized trials on PubMed; Methylene Blue has 131 and 382.
Based on 765 reports about Magnesium L-Threonate and 132 about Methylene Blue. Not medical advice.
| Magnesium L-Threonate Supplement | Methylene Blue Substance | |
|---|---|---|
| Users say it helped | 72%helped329 reports · high confidence | 64%helped37 reports · medium confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 82 / 210 | 131 / 382 |
| Mainly used for | ||
| Sleep % reporting improvement | 85% (166) | 50% (2) |
| Focus % reporting improvement | 97% (109) | 100% (23) |
| Anxiety % reporting improvement | 92% (78) | 100% (3) |
| Memory % reporting improvement | 93% (43) | 100% (4) |
| Mood % reporting improvement | 89% (36) | 100% (7) |
| Common side effects | vivid dreams, headache, drowsiness, stomach issues | green urine, color change, agitation, serotonin syndrome |
| Typical dose reported | 6 caps / daily | 0.5-5 mg / daily |
This review confirms that the quality of literature is substandard for physicians to make well-informed recommendations on usage of oral magnesium for older adults with insomnia. However, given that oral magnesium is very cheap and widely available, RCT evidence may support oral magnesium supplements (less than 1 g quantities given up to three times a day) for insomnia symptoms.
BMC Complement Med Ther, 2021 ↗“I just tried magnesium theronate the other day and I feel like a new person... My memory recall is better too. Emotions and anxiety have levelled DRASTICALLY.”
Among critically ill adults with septic shock, based on low-certainty evidence, MB may reduce short-term mortality, duration of vasopressors, and hospital length of stay, with no evidence of increased adverse events. Rigorous randomized trials evaluating the efficacy of MB in septic shock are needed.
Crit Care Explor, 2024 ↗“Seems to be doing something. My Dual N back scores are up. My social anxiety also seems to be getting better. I am taking 60mcg 3x daily approximately every 5 hours.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate