Kratom vs TB-500 for pain & inflammation
Short answer: For pain & inflammation, more users report improvement with Kratom — 93% of 28 reports, versus 84% of 168 for TB-500.
Kratom has 18 meta-analyses and 5 randomized trials on PubMed; TB-500 has 0 and 3.
Based on 421 reports about Kratom and 652 about TB-500. Not medical advice.
| Kratom Substance | TB-500 Peptide | |
|---|---|---|
| User score | 50 | 49 |
| Verdict | Mixed | Mostly positive |
| Positive of reports that state an outcome | 42% | 67% |
| Reports | 421 | 652 |
| Research | BResearch: Moderate | CResearch: Limited |
| Meta-analyses / RCTs | 18 / 5 | 0 / 3 |
| Mainly used for | ||
| Weight loss % reporting improvement | 50% (2) | 100% (8) |
| Appetite % reporting improvement | 100% (3) | 100% (2) |
| Focus % reporting improvement | 77% (31) | 50% (2) |
| Energy % reporting improvement | 78% (54) | 50% (4) |
| Sleep % reporting improvement | 71% (7) | 60% (5) |
| Anxiety % reporting improvement | 86% (69) | 29% (7) |
| Mood % reporting improvement | 85% (97) | 89% (9) |
| Memory % reporting improvement | 0% (5) | — |
| Performance % reporting improvement | 100% (3) | 100% (17) |
| Recovery % reporting improvement | — | 97% (208) |
| Pain & inflammation % reporting improvement | 93% (28) | 84% (168) |
| Digestion % reporting improvement | 33% (9) | 100% (2) |
| Libido % reporting improvement | 0% (12) | — |
| Hormones % reporting improvement | 22% (9) | — |
| Heart & lipids % reporting improvement | — | 60% (5) |
| Skin & hair % reporting improvement | — | 84% (19) |
| Immunity % reporting improvement | — | 60% (5) |
| Common side effects | withdrawal, dependence, addiction, tolerance | anxiety, fatigue, dizziness, allergic reaction |
| Typical dose reported | 4 g / 2x daily | Not listed |
KratomFull Kratom profile →
Latest review conclusion
Based on our analysis, patients using <20 g of kratom/d could be initiated on opioid agonist therapy with 4/1 mg-8/2 mg buprenorphine-naloxone/d, while patients using kratom doses >40 g/d could be initiated with 12/3 mg-16/4 mg of buprenorphine-naloxone/day.
J Addict Med, 2021 ↗What a user said
“Green or white Kratom powder. My productivity and overall mood have skyrocketed. I dose 4 grams once per day and it’s worked wonders.”
TB-500Full TB-500 profile →
What a user said
“They reduce neuroinflammation in the brain caused by either head injuries or drug abuse. Ive used them both for this and it works.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate