PlainPill

Kava vs Skullcap for anxiety

Short answer: For anxiety, more users report improvement with Skullcap — 100% of 31 reports, versus 93% of 196 for Kava.

Kava has 41 meta-analyses and 37 randomized trials on PubMed; Skullcap has 5 and 3.

Based on 431 reports about Kava and 97 about Skullcap. Not medical advice.

Kava
Supplement
Skullcap
Supplement
Users say it helped63%helped224 reports · high confidence81%helped46 reports · medium confidence
Verdict
Mostly positive
Mostly positive
ResearchAResearch: StrongBResearch: Moderate
Meta-analyses / RCTs41 / 375 / 3
Mainly used for
Anxiety
% reporting improvement
93% (196)100% (31)
Sleep
% reporting improvement
86% (37)100% (12)
Mood
% reporting improvement
80% (35)67% (3)
Pain & inflammation
% reporting improvement
100% (10)100% (2)
Focus
% reporting improvement
67% (6)—
Common side effectsdrowsiness, liver damage, stomach issues, irritabilitydysphoria, drowsiness, liver damage, unusual next
Typical dose reported60 mg kavalactone equivalent / daily2-4 g / PRN
Kava
Latest review conclusion

Numerous interactions between herbal medicines and conventional drugs have been documented. While the significance of many interactions is uncertain, several interactions, particularly those with St John's wort, may have serious clinical consequences.

Drugs, 2009 ↗
What a user said
“I felt insanely relaxed, any anxiety was dropped to 0, and I could think more clearly.”
Full Kava profile →
Skullcap
Latest review conclusion

Besides, no severe adverse effects was identified by CHM. CHM, especially classical Chinese herbal formulas, could be used as potential candidates for COVID-19 in this battle.

Pharmacol Res, 2020 ↗
What a user said
“St. John's Wort, Passion Flower, Hops, and Skullcap. My sleep improved with those.”
Full Skullcap profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate