Ephedrine vs Tirzepatide for weight loss
Short answer: For weight loss, more users report improvement with Ephedrine — 100% of 37 reports, versus 94% of 206 for Tirzepatide.
Ephedrine has 80 meta-analyses and 614 randomized trials on PubMed; Tirzepatide has 214 and 132.
Based on 265 reports about Ephedrine and 428 about Tirzepatide. Not medical advice.
| Ephedrine Substance | Tirzepatide Medication | |
|---|---|---|
| Users say it helped | 59%helped135 reports · high confidence | 75%helped287 reports · high confidence |
| Verdict | Mixed | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 80 / 614 | 214 / 132 |
| Mainly used for | ||
| Weight loss % reporting improvement | 100% (37) | 94% (206) |
| Energy % reporting improvement | 92% (86) | 44% (32) |
| Appetite % reporting improvement | 71% (28) | 84% (79) |
| Mood % reporting improvement | 100% (4) | 63% (27) |
| Focus % reporting improvement | 84% (25) | 50% (4) |
| Common side effects | jitteriness, anxiety, insomnia, blood pressure | nausea, fatigue, anhedonia, constipation |
| Typical dose reported | 24 mg / 3x daily | Not listed |
CMSs are an increasingly recognised group of genetically transmitted defects, which usually respond favorably to drugs enhancing the neuromuscular transmission. CMSs need to be differentiated from neuromuscular disorders due to muscle or nerve dysfunction.
Orphanet J Rare Dis, 2019 ↗“Ephedrine gives me tons of energy, makes me happy, positive, and talkative. It's an excellent pre-workout, though it doesn't suppress my appetite like it's supposed.”
This study shows that new anti-diabetic drugs, particularly GLP1-RA and Tirzepatide, are the most effective in inducing weight loss in patients with type 2 diabetes. Interestingly, exenatide appears to be the only GLP1-RA that induces a mild weight loss.
Pharmacol Res, 2021 ↗“Tirzepatide works so well! Do some research in the r/peptides subreddit and the r/tirzepatide subreddit. It's the most effective thing I've ever seen for appetite suppressant.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate