PlainPill

Curcumin vs Saffron for mood

Short answer: For mood, users rate them about the same: 96% report improvement with Curcumin (45 reports) and 92% with Saffron (165 reports).

Curcumin has 538 meta-analyses and 553 randomized trials on PubMed; Saffron has 88 and 119.

Based on 544 reports about Curcumin and 421 about Saffron. Not medical advice.

Curcumin
Supplement
Saffron
Supplement
Users say it helped61%helped180 reports · high confidence62%helped223 reports · high confidence
Verdict
Mostly positive
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs538 / 55388 / 119
Mainly used for
Mood
% reporting improvement
96% (45)92% (165)
Pain & inflammation
% reporting improvement
91% (104)100% (3)
Anxiety
% reporting improvement
93% (15)81% (84)
Focus
% reporting improvement
78% (9)79% (38)
Energy
% reporting improvement
83% (6)81% (21)
Common side effectsvivid dreams, headache, nausea, dht suppressionheadache, appetite suppression, insomnia, vivid dreams
Typical dose reported1000 mg / daily30 mg
Curcumin
Latest review conclusion

Curcumin and Curcuma longa Extract may improve symptoms and inflammation levels in people with arthritis. However, due to the low quality and small quantity of RCTs, the conclusions need to be interpreted carefully.

Front Immunol, 2022 ↗
What a user said
“I recently stopped taking Curcumin because of its affect on DHT and I was looking for an alternative measure to deal with inflammation as I feel it really helped with anxiety/depression.”
Full Curcumin profile →
Saffron
Latest review conclusion

Saffron demonstrates promise in improving ADHD symptoms, with an acceptable safety profile. Future well-designed multicentral studies are suggested.

J Atten Disord, 2024 ↗
What a user said
“I just sneak some into whatever soup we are having. I honestly think it has made a huge difference.”
Full Saffron profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate