Creatine vs Oxiracetam for memory
Short answer: For memory, more users report improvement with Oxiracetam — 100% of 23 reports, versus 91% of 70 for Creatine.
Creatine has 763 meta-analyses and 2,794 randomized trials on PubMed; Oxiracetam has 5 and 19.
Based on 1,564 reports about Creatine and 254 about Oxiracetam. Not medical advice.
| Creatine Supplement | Oxiracetam Supplement | |
|---|---|---|
| User score | 53 | 49 |
| Verdict | Mostly positive | Mostly positive |
| Positive of reports that state an outcome | 67% | 69% |
| Reports | 1,564 | 254 |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 763 / 2,794 | 5 / 19 |
| Mainly used for | ||
| Weight loss % reporting improvement | 82% (11) | — |
| Appetite % reporting improvement | 67% (3) | — |
| Focus % reporting improvement | 92% (211) | 91% (55) |
| Energy % reporting improvement | 97% (205) | 100% (14) |
| Sleep % reporting improvement | 27% (73) | — |
| Anxiety % reporting improvement | 62% (24) | 62% (8) |
| Mood % reporting improvement | 85% (103) | 64% (11) |
| Memory % reporting improvement | 91% (70) | 100% (23) |
| Performance % reporting improvement | 97% (320) | 100% (5) |
| Recovery % reporting improvement | 98% (62) | — |
| Pain & inflammation % reporting improvement | 50% (4) | — |
| Digestion % reporting improvement | 0% (6) | — |
| Libido % reporting improvement | 82% (11) | — |
| Hormones % reporting improvement | 75% (12) | — |
| Blood sugar % reporting improvement | 100% (3) | — |
| Heart & lipids % reporting improvement | 67% (6) | — |
| Skin & hair % reporting improvement | 17% (12) | — |
| Longevity % reporting improvement | 100% (4) | — |
| Common side effects | hair loss, stomach issues, insomnia, water retention | hypomania, brain fog, anxiety, tolerance |
| Typical dose reported | daily | as needed |
The results of the meta-analysis suggest that creatine supplementation did not significantly alter serum creatinine levels (standardized mean difference = 0.48, 95% confidence interval 0.24-0.73, P = .001, I2 = 22%), and did not alter plasma urea values (standardized mean difference = 1.10, 95% confidence interval 0.34-1.85, P = .004, I2 = 28%). The findings indicate that creatine supplementation does not induce renal damage in the studied amounts and durations.
J Ren Nutr, 2019 ↗“I actually feel a lot better. Mentally clearer and more balanced, like I have my brain back.”
This study enhances the understanding of the relative benefits and risks associated with various VaD treatments, providing a valuable reference for clinical decision-making.
Front Pharmacol, 2024 ↗“Oxi gave me a significant increase in focus, to the point where I could work for 2-3 hours without even checking facebook. / It also helped me with memory (was clearly retaining more info in both short-term and long-term).”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate