Creatine vs Nicotine for focus
Short answer: For focus, users rate them about the same: 93% report improvement with Creatine (249 reports) and 92% with Nicotine (244 reports).
Creatine has 763 meta-analyses and 2,794 randomized trials on PubMed; Nicotine has 1,323 and 3,241.
Based on 2,279 reports about Creatine and 586 about Nicotine. Not medical advice.
| Creatine Supplement | Nicotine Substance | |
|---|---|---|
| Users say it helped | 72%helped1,048 reports · high confidence | 38%helped352 reports · high confidence |
| Verdict | Mostly positive | Mixed |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 763 / 2,794 | 1,323 / 3,241 |
| Mainly used for | ||
| Performance % reporting improvement | 98% (542) | 50% (8) |
| Focus % reporting improvement | 93% (249) | 92% (244) |
| Energy % reporting improvement | 97% (268) | 94% (84) |
| Mood % reporting improvement | 87% (125) | 65% (54) |
| Memory % reporting improvement | 93% (85) | 79% (29) |
| Common side effects | stomach issues, hair loss, insomnia, water retention | addiction, anxiety, nausea, tolerance |
| Typical dose reported | 5 g / daily | 2 mg / cycled |
The results of the meta-analysis suggest that creatine supplementation did not significantly alter serum creatinine levels (standardized mean difference = 0.48, 95% confidence interval 0.24-0.73, P = .001, I2 = 22%), and did not alter plasma urea values (standardized mean difference = 1.10, 95% confidence interval 0.34-1.85, P = .004, I2 = 28%). The findings indicate that creatine supplementation does not induce renal damage in the studied amounts and durations.
J Ren Nutr, 2019 ↗“I actually feel a lot better. Mentally clearer and more balanced, like I have my brain back.”
It provides crucial new knowledge about the efficacy of such interventions in preventing e-cigarette use and improving other outcomes (e.g., tobacco use, knowledge, intentions, attitudes, and mental health) among adolescents and the key characteristics associated with efficacious interventions. Our findings have important practical implications, highlighting future research directions for the development and evaluation of e-cigarette preventive interventions, along with the need to provide support to schools to help them identify and adopt evidence-based programs.
Prev Sci, 2024 ↗“Nicotine gum/pouches have been helpful for me especially when I am trying to focus at work.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate