PlainPill

Berberine vs Cinnamon for blood sugar

Short answer: For blood sugar, more users report improvement with Cinnamon — 100% of 12 reports, versus 87% of 82 for Berberine.

Berberine has 109 meta-analyses and 110 randomized trials on PubMed; Cinnamon has 75 and 95.

Based on 373 reports about Berberine and 54 about Cinnamon. Not medical advice.

Berberine
Supplement
Cinnamon
Supplement
Users say it helped56%helped119 reports · high confidence68%helped10 reports · few reports
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs109 / 11075 / 95
Mainly used for
Blood sugar
% reporting improvement
87% (82)100% (12)
Weight loss
% reporting improvement
83% (24)—
Energy
% reporting improvement
91% (23)—
Appetite
% reporting improvement
84% (19)—
Digestion
% reporting improvement
60% (15)—
Common side effectsstomach issues, constipation, anxiety, brain fogcoumarin toxicity
Typical dose reported400-500 mg / daily1 teaspoon
Berberine
Latest review conclusion

Treatment with berberine may be safe since it does not increase the incidence of total adverse events and the risk of hypoglycemia. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=292975, identifier CRD42021292975.

Front Pharmacol, 2022 ↗
What a user said
“I started berberine and inositol, and began having energy that I did not have before. Somehow, my recovery after working out wasn't as long either.”
Full Berberine profile →
Cinnamon
Latest review conclusion

The consumption of cinnamon is associated with a statistically significant decrease in levels of fasting plasma glucose, total cholesterol, LDL-C, and triglyceride levels, and an increase in HDL-C levels; however, no significant effect on hemoglobin A1c was found. The high degree of heterogeneity may limit the ability to apply these results to patient care, because the preferred dose and duration of therapy are unclear.

Ann Fam Med, 2013 ↗
What a user said
“And I'll add: cinnamon, C3G, ALA, possibly also banana leaf, Benfotiamine and Fucoxanthin”
Full Cinnamon profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate