Armodafinil vs Lisdexamfetamine for focus
Short answer: For focus, users rate them about the same: 87% report improvement with Armodafinil (76 reports) and 87% with Lisdexamfetamine (200 reports).
Armodafinil has 34 meta-analyses and 44 randomized trials on PubMed; Lisdexamfetamine has 58 and 112.
Based on 222 reports about Armodafinil and 439 about Lisdexamfetamine. Not medical advice.
| Armodafinil Medication | Lisdexamfetamine Medication | |
|---|---|---|
| Users say it helped | 65%helped113 reports · high confidence | 41%helped281 reports · high confidence |
| Verdict | Mostly positive | Mixed |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 34 / 44 | 58 / 112 |
| Mainly used for | ||
| Focus % reporting improvement | 87% (76) | 87% (200) |
| Energy % reporting improvement | 95% (61) | 61% (62) |
| Mood % reporting improvement | 77% (13) | 50% (82) |
| Anxiety % reporting improvement | 50% (12) | 39% (36) |
| Sleep % reporting improvement | 20% (5) | 12% (17) |
| Common side effects | anxiety, insomnia, jitteriness, headache | anxiety, insomnia, fatigue, irritability |
| Typical dose reported | Not listed | Not listed |
“I experience significantly less anxiety with armodafinil than modafinil, and some others do as well.”
Our findings represent the most comprehensive available evidence base to inform patients, families, clinicians, guideline developers, and policymakers on the choice of ADHD medications across age groups. Taking into account both efficacy and safety, evidence from this meta-analysis supports methylphenidate in children and adolescents, and amphetamines in adults, as preferred first-choice medications for the short-term treatment of ADHD. New research should be funded urgently to assess long-term effects of these drugs.
Lancet Psychiatry, 2018 ↗“It's been a game changer for my focus and energy levels, really brought me back to life.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate