PlainPill

Amphetamine vs Armodafinil for focus

Short answer: For focus, users rate them about the same: 85% report improvement with Amphetamine (428 reports) and 87% with Armodafinil (76 reports).

Amphetamine has 258 meta-analyses and 521 randomized trials on PubMed; Armodafinil has 34 and 44.

Based on 878 reports about Amphetamine and 222 about Armodafinil. Not medical advice.

Amphetamine
Medication
Armodafinil
Medication
Users say it helped35%helped606 reports · high confidence65%helped113 reports · high confidence
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs258 / 52134 / 44
Mainly used for
Focus
% reporting improvement
85% (428)87% (76)
Energy
% reporting improvement
75% (146)95% (61)
Mood
% reporting improvement
48% (132)77% (13)
Anxiety
% reporting improvement
38% (56)50% (12)
Sleep
% reporting improvement
9% (35)20% (5)
Common side effectstolerance, anxiety, insomnia, jitterinessanxiety, insomnia, jitteriness, headache
Typical dose reportedNot listedNot listed
Amphetamine
Latest review conclusion

Overall, despite a class effect of improving clinical response relative to placebo, there were few differences among the individual ADHD pharmacotherapies, and most studies were at risk of at least one important source of bias. Furthermore, the certainty of the evidence was very low to low for all outcomes, and there was limited reporting of long-term adverse events. As such, the choice between ADHD pharmacotherapies may depend on individual patient considerations, and future studies should assess the long-term effects of individual pharmacotherapies on patient-important outcomes, including qu

PLoS One, 2020 ↗
What a user said
“Unfortunately the only thing that's ever works for me was using adderall. I didn't feel hungry until 3 pm and it was perfect.”
Full Amphetamine profile →
Armodafinil
Latest review conclusion

J Clin Sleep Med. 2021;17(9):1881-1893.

J Clin Sleep Med, 2021 ↗
What a user said
“I experience significantly less anxiety with armodafinil than modafinil, and some others do as well.”
Full Armodafinil profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate