Amphetamine vs Citicoline for focus
Short answer: For focus, users rate them about the same: 85% report improvement with Amphetamine (428 reports) and 89% with Citicoline (103 reports).
Amphetamine has 258 meta-analyses and 521 randomized trials on PubMed; Citicoline has 39 and 106.
Based on 878 reports about Amphetamine and 681 about Citicoline. Not medical advice.
| Amphetamine Medication | Citicoline Supplement | |
|---|---|---|
| Users say it helped | 35%helped606 reports · high confidence | 63%helped218 reports · high confidence |
| Verdict | Mixed | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 258 / 521 | 39 / 106 |
| Mainly used for | ||
| Focus % reporting improvement | 85% (428) | 89% (103) |
| Mood % reporting improvement | 48% (132) | 57% (46) |
| Energy % reporting improvement | 75% (146) | 95% (19) |
| Memory % reporting improvement | 50% (32) | 94% (47) |
| Anxiety % reporting improvement | 38% (56) | 36% (11) |
| Common side effects | tolerance, anxiety, insomnia, jitteriness | depression, headache, anxiety, irritability |
| Typical dose reported | Not listed | 500 mg |
Overall, despite a class effect of improving clinical response relative to placebo, there were few differences among the individual ADHD pharmacotherapies, and most studies were at risk of at least one important source of bias. Furthermore, the certainty of the evidence was very low to low for all outcomes, and there was limited reporting of long-term adverse events. As such, the choice between ADHD pharmacotherapies may depend on individual patient considerations, and future studies should assess the long-term effects of individual pharmacotherapies on patient-important outcomes, including qu
PLoS One, 2020 ↗“Unfortunately the only thing that's ever works for me was using adderall. I didn't feel hungry until 3 pm and it was perfect.”
The general quality of the studies, however, is poor with significant risk of bias in favor of the intervention. Other: PubMed and the Cochrane Library.
Nutrients, 2023 ↗“With standard NAC, Piracetam, and Choline I started to feel incredibly balanced, mood stabilized, better focus, and memory retention.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate