Across 630 first-hand reports, people mentioned a side effect 36 times (about 6 per 100 reports). The most common: acne, anxiety, jitteriness. User reports show what people notice — they can't tell you whether Vitamin B12 is safe for you.
“I tried so many things for depression like saffron rhodiola tyrosine omega 3 methylfolate B12 taurine theanine NAC inositol b complex magnesium nothing helps it.”
“I'm still taking Magnesium, Vitamin D and the B12 regularly, however I do not notice any difference so far.”
“Everytime I go up in dose (and sometimes, down) with methyl B12, I experience a few days where I feel very energetic, and everything is just great.”
“Methyl B12 destroys me. It makes me feel on edge with no ability to tolerate stress.”
Conclusion: The evidence suggests an association between elevated B12 with a higher risk of cancer, with risk ratios ranging 1,88 to 5,9. There was less consistent evidence linking vitamin B12 and mortality.
Conclusion: In conclusion, maintaining optimum serum levels of nutrients and vitamins, either through a balanced and healthy diet consuming fresh fruits, vegetables, and fats or by taking appropriate supplementation, is essential in maintaining optimal health-related quality of life and reducing the risk for women during the menopausal transition and after menopause. Nevertheless, more recent studies need to be assessed to formulate adequate recommendations to achieve positive clinical outcomes.