What are the side effects of Thiamine Hcl?

Users most often report orthostatic hypotension, respiratory muscle, blurred vision, incoordination, head pressure. Side effects came up 8 times across 9 reports.

Thiamine Hcl side effects

Q: Is Thiamine Hcl safe?

User reports can't establish safety. PubMed lists 116 meta-analyses and 155 randomized trials. Talk to a doctor or pharmacist, especially if you take other medication.

Across 9 first-hand reports, people mentioned a side effect 8 times (about 89 per 100 reports). The most common: orthostatic hypotension, respiratory muscle, blurred vision. User reports show what people notice — they can't tell you whether Thiamine Hcl is safe for you.

Reported side effects

orthostatic hypotension1

respiratory muscle1

blurred vision1

incoordination1

head pressure1

night sweats1

chest pain1

tingling1

In their own words

“if it's version with benfo+small dose thiamine HCL I would get some histamine symtoms.”

MixedRead the discussion ↗

Is Thiamine Hcl safe? What the research covers

AResearch: Strong116 meta-analyses · 155 randomized trials on PubMed

J Neurol · 2019

Conclusion: At present, it is unclear what the pathogenetic mechanisms for the development of neuropathy amongst those who chronically abuse alcohol are, and therefore, it is unknown whether it is attributed to the direct toxic effects of ethanol or another currently unidentified factor. There is presently sparse data to support a particular management strategy in alcohol-related peripheral neuropathy, but the limited data available appears to support the use of vitamin supplementation, particularly of B-vitamin regimens inclusive of thiamine.

Nutrients · 2022

Vitamin Supplementation and Dementia: A Systematic Review

Conclusion: The findings of this systematic review suggest that supplementation of B Complex vitamins, especially folic acid, may have a positive effect on delaying and preventing the risk of cognitive decline. Ascorbic acid and a high dose of vitamin E, when given separately, also showed positive effects on cognitive performance, but there is not sufficient evidence to support their use. The results of vitamin D supplementation trials are not conclusive in assessing the potential benefits that vitamin D might have on cognition.

BMJ Clin Evid · 2007

Dysmenorrhoea

Conclusion: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupressure, acupuncture, aspirin, behavioural interventions, combined oral contraceptives, compound analgesics, fish oil, herbal remedies, magnesium, magnets, non-steroidal anti-inflammatory drugs, paracetamol, spinal manipulation, surgical interruption of pelvic nerve pathways, thiamine, toki-shakuyaku-san, topical heat, transcutaneous electrical nerve stimulation (TENS), vitamin B12, and vitamin E.