Conclusion: Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients' sexual confidence. Furthermore, patients and their partners prefer tadalafil to sildenafil. Hence, tadalafil may be a better choice for ED treatment.
Tadalafil side effects
Across 253 first-hand reports, people mentioned a side effect 37 times (about 15 per 100 reports). The most common: headache, stuffy nose, heartburn. User reports show what people notice — they can't tell you whether Tadalafil is safe for you.
Reported side effects
headache11
stuffy nose8
heartburn6
lower back4
acid reflux3
tinnitus2
stomach issues2
eye pain1
In their own words
“After a week of 2.5 mg twice a day, this is my favourite drug ever. My brain fog has gone...My mood is so much better, similar to an SSRI but without the flat feeling.”
“I use it sporadically as a preworkout, 5mg before gym, gets a nice pump going - I always get a stuffy nose and that's about it from side effects that Ive noticed.”
“It's probably the only drug I've ever taken that's improved my overall mood and impacted my mental health positively. People say it's because the improved blood flow in the brain.”
“Definitely works!! My trap muscles got really achey like some people warned would happen but only a couple times.”
“I've tried and currently am trying Cialis (doesn't really help because my arousal is clouded by anxiety)”
“I take 5mg almost daily... It also helps me keep erections... great for pumps in the gym... Aren't headaches the #1 side effect of daily Cialis?? I actually quit low dose Cialis because of the headaches”
Is Tadalafil safe? What the research covers
AResearch: Strong120 meta-analyses · 347 randomized trials on PubMed
Int Urol Nephrol · 2017
Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysisBMJ Clin Evid · 2011
Erectile dysfunctionConclusion: In this systematic review we present information relating to the effectiveness and safety of the following interventions: alprostadil (intracavernosal, intraurethral, topical), cognitive behavioural therapy, ginseng, papaverine, papaverine plus phentolamine (bimix), papaverine plus phentolamine plus alprostadil (trimix), penile prostheses, phosphodiesterase inhibitors (sildenafil, tadalafil, vardenafil), psychosexual counselling, vacuum devices, and yohimbine.