SS-31 reviews: what real users say
We read 121 first-hand mentions of SS-31 from health and supplement communities. 39 of them say clearly how it went — and 69% of those say it helped.
Where people say it works: energy (82% of 28).
Most common complaints: brain fog, irritability, itching at, rash at, headache. All side effects →
High-risk compound. Not an approved supplement; nothing here is a recommendation to use it.
Positive experiences
“Using SS-31 50mg 3x weekly right now... Day of injection have loads of energy... Noticeably more exercise stamina... I literally feel 10-20 years younger.”
“Energy levels are way up, I don't have any midday crash, I'm 49 years old but feel like my battery got replaced by a much younger person's battery.”
“SS-31 has raised my energy baseline by 15-20% after one 3-week cycle of 10mg/day. I have ME/CFS (Long covid)”
“I've done four rounds of SS‑31 (2 mg daily for 4–6 weeks) and four rounds of MOTS‑C (2 mg M–F) since spring 2025. So far I've had great results and zero side effects.”
“he said the therapeutic dose was 4mg/day (not 40mg)... I've been doing 4mg/day as directed for about 60 days with good results.”
“I have felt like TA-1, ss31 and then MOTs-C have been helpful for getting me out of the same type of funk.”
Negative and mixed experiences
“I ran SS-31 for a month before starting MOTS. I’m now running both concurrently. Honestly, I haven’t felt a damn thing from either.”
“I take ss31 and ta1 daily. They really help but... If you don’t have mito issues and are younger than 40, it’s going to do nothing.”
“I ran SS-31 just because being old, I think it really helped with my overall energy.”
“it felt like my dopamine got blunted, like my executive function just switched off”
“I think ss-31 gave me a perceived increase just because I had more energy not actually made me stronger”
“I ran SS31 at 5mg daily a while back and didn’t feel much from it but I’m doing it again just now at 10mg daily and definitely feeling the energy”
Quotes are verbatim and link to the original public discussion. Information only — not medical advice. How we collect reports