What are the side effects of Quetiapine?

Users most often report drowsiness, weight gain, fatigue, tolerance, brain fog. Side effects came up 20 times across 57 reports.

User reports can't establish safety. PubMed lists 468 meta-analyses and 524 randomized trials. Talk to a doctor or pharmacist, especially if you take other medication.

Quetiapine side effects

Across 57 first-hand reports, people mentioned a side effect 20 times (about 35 per 100 reports). The most common: drowsiness, weight gain, fatigue. User reports show what people notice — they can't tell you whether Quetiapine is safe for you.

Reported side effects

drowsiness7

weight gain3

fatigue3

tolerance2

brain fog2

fast resting1

vasoconstriction1

panic1

In their own words

“it turned me into a complete fucking zombie with no emotional affect. I also gained 30 lbs in those 3 months.”

MixedRead the discussion ↗

“Seroquel is fucked up, nearly killed me...Sorry to hear about your experience with Seroquel. It's worked pretty good for me.”

HelpedRead the discussion ↗

“I absolutely believe the quitiapene helps prevent me from tolerating my Adderall dose too much... However, it numbs the effect of Adderall overall”

MixedRead the discussion ↗

“my seroquel stopped working and I had to go up on that, which is causing my appetite to come back and I'm starting to gain weight”

Didn't helpRead the discussion ↗

“Seroquel, which improved mood, but took away all motivation and made me very sleepy”

Didn't helpRead the discussion ↗

“Readily puts me to sleep at the cost of an extremely groggy morning; no impact on anxiety”

Didn't helpRead the discussion ↗

Is Quetiapine safe? What the research covers

AResearch: Strong468 meta-analyses · 524 randomized trials on PubMed

Lancet Psychiatry · 2023

Comparative efficacy and tolerability of pharmacological interventions for acute bipolar depression in adults: a systematic review and network meta-analysis

Conclusion: This is, to our knowledge, the largest network meta-analysis of pharmacotherapy for bipolar depression to date. Olanzapine plus fluoxetine, quetiapine, olanzapine, lurasidone, lumateperone, cariprazine, and lamotrigine were found to be more efficacious than placebo in adults with acute bipolar depression, with good confidence in the evidence, and to differ in their side-effect profiles. These findings can inform evidence-based care and the development of treatment guidelines internationally.