Across 37 first-hand reports, people mentioned a side effect 9 times (about 24 per 100 reports). The most common: anxiety, irritability, jitteriness. User reports show what people notice — they can't tell you whether Pseudoephedrine is safe for you.
“Pseudophedrine in claritin d and other decongestion meds. However it makes me feel very scatter brained.”
“Low dose 10mg pseudoephedrine has been a lifesaver for my ADD, and helped me kick Adderall which was causing too many sides.”
“I took it with coffee and barely id anything (2 pills every few hours to avoid acetoaminophen toxicity) and now today i tried nicotine gum and its literally between my gums as i write this reddit and sadly nothing”
“Nicotine and 7 hydro and pseudoephedrine have probably been the best cognitive boosters for me.”
“took pseudoephedrine for 4-5 years daily. very effective...however, over time I started to develop muscle cramps...cognition-wise the decline set in after two years”
“Yes it's a stimulant... Downside is it increases your blood pressure and my resting heart rate goes up by 5-10bpm when I take it over a few days”
Conclusion: In this systematic review we present information relating to the effectiveness and safety of the following interventions: analgesics or anti-inflammatory drugs, antibiotics, antihistamines, decongestants (norephedrine, oxymetazoline, or pseudoephedrine), decongestants plus antihistamine, echinacea, steam inhalation, vitamin C, and zinc (intranasal gel or lozenges).
Conclusion: In this systematic review we present information relating to the effectiveness and safety of the following interventions: antibiotics (amoxicillin, amoxicillin-clavulanic acid [co-amoxiclav], doxycycline, cephalosporins, macrolides; different doses, long-course regimens), antihistamines, decongestants (xylometazoline, phenylephrine, pseudoephedrine), saline nasal washes, steam inhalation, and topical corticosteroids (intranasal).
Conclusion: In this systematic review we present information relating to the effectiveness and safety of the following interventions: antibiotics (amoxicillin, co-amoxiclav, doxycycline, cephalosporins, macrolides, different doses [amoxicillin, co-amoxiclav, doxycycline, cephalosporins, macrolides], long-course regimens), antihistamines, cephalosporins or macrolides, decongestants (xylometazoline, phenylephrine, pseudoephedrine), doxycycline, saline nasal washes, steam inhalation, and topical corticosteroids (intra-nasal).