Conclusion: Although 22 trials could be included in this review, the evidence provided is limited and mostly not relevant to clinicians or consumers. Overall, although there was low risk of attrition and selective data reporting bias within the trials, the trials themselves were not adequately powered and need more substantial follow-up periods. There is a need for larger trials with longer periods of follow-up to be conducted. Outcomes should be meaningful for those with schizophrenia, and include measures of improvement and relapse (not just rating scale scores), functioning and quality of life and acce
N-Acetyl-Cysteine side effects
Across 22 first-hand reports, people mentioned a side effect 5 times (about 23 per 100 reports). The most common: brain fog, malaise, rash. User reports show what people notice — they can't tell you whether N-Acetyl-Cysteine is safe for you.
Reported side effects
brain fog1
malaise1
rash1
vivid dreams1
racing thoughts1
In their own words
“I took N-Acetyl-Cysteine over a course of 8 months and stopped three months ago. I got side effects from the dopamine raising effect of NAC and got really wild nightmares every night and racing thoughts”
Is N-Acetyl-Cysteine safe? What the research covers
AResearch: Strong67 meta-analyses · 130 randomized trials on PubMed
Cochrane Database Syst Rev · 2016
Antioxidant treatments for schizophreniaCochrane Database Syst Rev · 2017
Antioxidants for female subfertilityConclusion: In this review, there was very low-quality evidence to show that taking an antioxidant may provide benefit for subfertile women, but insufficient evidence to draw any conclusions about adverse events. At this time, there is limited evidence in support of supplemental oral antioxidants for subfertile women.