What are the side effects of Mirtazapine?

Users most often report drowsiness, fatigue, weight gain, brain fog, rebound insomnia. Side effects came up 25 times across 93 reports.

User reports can't establish safety. PubMed lists 174 meta-analyses and 262 randomized trials. Talk to a doctor or pharmacist, especially if you take other medication.

Mirtazapine side effects

Across 93 first-hand reports, people mentioned a side effect 25 times (about 27 per 100 reports). The most common: drowsiness, fatigue, weight gain. User reports show what people notice — they can't tell you whether Mirtazapine is safe for you.

Reported side effects

drowsiness6

fatigue5

weight gain4

brain fog3

rebound insomnia2

tolerance2

rls exacerbation2

pssd1

In their own words

“Mirtazapine worked great for me, I'd credit it with saving my life.”

HelpedRead the discussion ↗

“The only one that really helped me was mirtazapine but I piled on the weight.”

HelpedRead the discussion ↗

“A med like Remeron (I had HORRIBLE side effects) uses several of my mutated/broken metabolizers.”

Didn't helpRead the discussion ↗

“I tried Mirtazapine, it only worked for 2-3 days, it knocked me out on the 1st day, I was very tired the next day, on the 2nd day it worked less then on the 3rd day it didn't work.”

MixedRead the discussion ↗

“mirtazapine (Remeron) and it genuinely helped me. Sadly, my body was building a tolerance for it within that six month period.”

MixedRead the discussion ↗

“I take Mirtazapine and Gabapentin for sleep which have lost their efficacy for the most part.”

Didn't helpRead the discussion ↗

Is Mirtazapine safe? What the research covers

AResearch: Strong174 meta-analyses · 262 randomized trials on PubMed

Br J Clin Pharmacol · 2021

Drug-drug interactions with warfarin: A systematic review and meta-analysis

Conclusion: This review found low to moderate certainty evidence supporting the interaction between warfarin and a small group of medications, which result in increased bleeding risk. PPIs are associated with reduced hospitalization for upper GI bleeding for patients taking warfarin. Further studies are required to better understand drug-drug interactions leading to thromboembolic outcomes or death.