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Lithium side effects

Across 69 first-hand reports, people mentioned a side effect 8 times (about 12 per 100 reports). The most common: sickness, brain fog, tremors. User reports show what people notice — they can't tell you whether Lithium is safe for you.

Reported side effects

sickness1
brain fog1
tremors1
rls1
neck twitching1
headache1
apathy1
drowsiness1

In their own words

“I'm dumber than ever on lithium... Lithium is either interphering with my Adderall or the cognitive dampening is cancelling out the focus and alertness benefits.”
Didn't helpRead the discussion ↗
“Lithium was the only supplement that I took that produced almost the exact depressive results you describe with AlphaGPC.”
Didn't helpRead the discussion ↗
“When I take 5mg of lithium orotate it gives me a feeling of apathy, but reduces my ability to experience pleasure (what is called anhedonia).”
MixedRead the discussion ↗
“For my BP2 I'm taking lithium and effexor and I've never felt more stable in my life.”
HelpedRead the discussion ↗
“was put on Lithium which helped tremendously, but then started to give me really strange side effects (tremors, RLS, neck twitching, migraines), so I had to stop”
MixedRead the discussion ↗
“2.5mg lithium once or twice per week works well for me.”
HelpedRead the discussion ↗

Is Lithium safe? What the research covers

AResearch: Strong581 meta-analyses · 979 randomized trials on PubMed
Ageing Res Rev · 2024
Comparative efficacy, tolerability and acceptability of donanemab, lecanemab, aducanumab and lithium on cognitive function in mild cognitive impairment and Alzheimer's disease: A systematic review and network meta-analysis

Conclusion: Although it is yet to be determined which is more effective between lithium or lecanemab or donanemab, lithium may be more effective than aducanumab. Aducanumab, lecanemab and donanemab do not appear to differ in their effectiveness on cognitive function. Low-dose lithium may be safer than aducanumab, lecanemab and donanemab.

Lithium side effects: what 69 users report — PlainPill