PlainPill

Lions Mane 8:1

People mainly take Lions Mane 8:1 for focus, memory. Based on 15 first-hand reports and 0 meta-analyses & systematic reviews in the medical literature. Ranked #308 of 3,539 overall.

40
User score
Mixed
33% positive27% mixed7% negative33% unclear

Of reports that state an outcome, 49% are positive.

Clinical research
DNo human trials found
0
meta-analyses
0
RCTs
0
papers

What Lions Mane 8:1 does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

DNo human trials found

No randomized controlled trials in humans found on PubMed. The grade measures how much human research exists — read the conclusions below for what it found.

No meta-analyses or systematic reviews published yet — 0 randomized trials found.

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

1 gdaily
alternate daysas reported
500 mgmorning
at nightas reported
cycledas reported
500-1000 mgdaily

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

“I also tried both RM and ND lion's mane, and I got better results with ND's (but I was taking the 8:1 extract from ND)”
HelpedRead the discussion ↗
“It’s been long time, but I did use lion’s mane at night. Nothing notable happened.”
Didn't helpRead the discussion ↗
“I did a cycle of real mushrooms lion’s mane and barely felt anything. I'm a few weeks into ND 8:1 extract, and I'm very impressed thus far.”
MixedRead the discussion ↗
“Have you tried Lions Mane 8:1? It works well for me”
HelpedRead the discussion ↗
Top discussions (5)

Other options for focus

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate