L-Glutamine side effects
Across 141 first-hand reports, people mentioned a side effect 10 times (about 7 per 100 reports). The most common: stomach issues, anxiety, weird feeling. User reports show what people notice — they can't tell you whether L-Glutamine is safe for you.
Reported side effects
stomach issues2
anxiety2
weird feeling1
glutamate spikes1
insomnia1
jitteriness1
panic attack1
depression1
What got worse for some people
In their own words
“I've tried glutamine in doses of up to 10 grams, but I've not noticed any anti-anxiety effects.”
“Today I mixed in 5g of L-glutamine with my protein powder and almost immediately felt light-headed, with tingly hands, followed by exhaustion.”
“It worked amazingly and all my bloating was gone but it gave me the wprst panic attacks within 3 days of using it.”
“I find vastly improved recovery with it...the difference in how sore I am is major. / I got a massive depression after taking this for a few days”
Is L-Glutamine safe? What the research covers
AResearch: Strong19 meta-analyses · 117 randomized trials on PubMed
None of the top reviews we found focus on safety. All research on L-Glutamine.