Conclusion: Supplementation of some but not all micronutrients may benefit cardiometabolic health. This study highlights the importance of micronutrient diversity and the balance of benefits and risks to promote and maintain cardiovascular health in diverse populations. (Antioxidant Supplementation in the Prevention and Treatment of Cardiovascular Diseases; CRD42022315165).
L-Arginine side effects
Across 211 first-hand reports, people mentioned a side effect 16 times (about 8 per 100 reports). The most common: diarrhea, stomach issues, chest pain. User reports show what people notice — they can't tell you whether L-Arginine is safe for you.
Reported side effects
In their own words
“I tried so many things – L-Arginine, Citrulline, Zinc, Omega-3s, training, clean diet. Some things helped a bit, but nothing really fixed it.”
“I also started taking L-Arginine with it as I had a bunch of pills but to be honest I didn't notice any added pump at all.”
“I tried different forms and dosages of Magnesium, Zinc, L-Tyrosine, melatonin, L-Arginine, ALPHA-GPC... most of them didn't provide any meaningful and noticeable benefits”
“two weeks of arginine supplementation seemed like it rolled back easily a year or two of old injuries... best sleep of my life... bite my tongue more often”
Is L-Arginine safe? What the research covers
Conclusion: L-Arg displays biological activities in pregnancies complicated by HDP and growth restriction, both in women and animal models. L-Arg administration is safe and could be a candidate as an intervention beneficial to maternal and fetal outcomes, at least in moderate clinical disorders.
Conclusion: The increased cardiovascular risk in menopause stems from the exaggerated effects of changing physiology on the cardiovascular system affecting peripheral, cardiac and cerebrovascular beds. The differential effects of menopause on cardiovascular disease at the subclinical, biochemical and molecular levels form the highlights of this review.