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Ibuprofen side effects

Across 83 first-hand reports, people mentioned a side effect 14 times (about 17 per 100 reports). The most common: stomach issues, headache, stomach ulcers. User reports show what people notice — they can't tell you whether Ibuprofen is safe for you.

Reported side effects

stomach issues7
headache1
stomach ulcers1
liver toxicity1
ulcers1
heart attack1
stroke1
high blood1

In their own words

“I find curcumin works just as well, if not better, than ibuprofen.”
MixedRead the discussion ↗
“I tried paracetamol, ibuprofen, tramadol(all painkillers) and methyl salicylate to decrease inflammation prescribed by my doctor but nothing is working.”
Didn't helpRead the discussion ↗
“ibuprofen and weed is supposed to be a good way to inhibit memory loss but I didn't notice much of an effect when I tried.”
Didn't helpRead the discussion ↗
“3 days ago I tried 400 mg ibuprofen and I got a much milder version from 2 weeks ago: brain zaps, increased anxiety, high heart rate and elevated BP”
Didn't helpRead the discussion ↗

Is Ibuprofen safe? What the research covers

AResearch: Strong511 meta-analyses · 1,743 randomized trials on PubMed
BMJ · 2024
Comparative effects of drug interventions for the acute management of migraine episodes in adults: systematic review and network meta-analysis

Conclusion: Overall, eletriptan, rizatriptan, sumatriptan, and zolmitriptan had the best profiles and they were more efficacious than the recently marketed drugs lasmiditan, rimegepant, and ubrogepant. Although cost effectiveness analyses are warranted and careful consideration should be given to patients with a high risk cardiovascular profile, the most effective triptans should be considered as preferred acute treatment for migraine and included in the WHO List of Essential Medicines to promote global accessibility and uniform standards of care.

Cochrane Database Syst Rev · 2020
Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants

Conclusion: Ibuprofen is as effective as indomethacin in closing a PDA. Ibuprofen reduces the risk of NEC and transient renal insufficiency. Therefore, of these two drugs, ibuprofen appears to be the drug of choice. The effectiveness of ibuprofen versus paracetamol is assessed in a separate review. Oro-gastric administration of ibuprofen appears as effective as IV administration. To make further recommendations, studies are needed to assess the effectiveness of high-dose versus standard-dose ibuprofen, early versus expectant administration of ibuprofen, echocardiographically-guided versus standard IV ibup

Ibuprofen side effects: what 83 users report — PlainPill